Redox-Magnetohydrodynamic Microfluidics Without Channels and Compatible with Electrochemical Detection Under Immunoassay Conditions

Electrochemical detection for paper-based microfluidics.

We report the first demonstration of electrochemical detection for paper-based microfluidic devices. Photolithography was used to make microfluidic channels on filter paper, and screen-printing technology was used to fabricate electrodes on the paper-based microfluidic devices. Screen-printed electrodes on paper were characterized using cyclic voltammetry to demonstrate the basic electrochemica...

Electrochemical immunoassay platform for high sensitivity protein detection based on redox-modified carbon nanotube labels.

We report a highly sensitive immunoassay protocol based on the use of redox-modified multi-walled carbon nanotubes (MWNTs) as electrochemical labels. The MWNTs were coated with methylene blue (MB) at an optically-determined loading of 3.41 × 10(-3) mol g(-1), and were then attached to secondary antibodies (Ab(2)) by adsorption. As a model analyte mouse IgG was collected by primary antibody (Ab(...

Electrochemical Processes in Microfluidics Systems under Ac Electric Fields

Magnetohydrodynamic flow of RedOx electrolyte

Magnetohydrodynamic MHD flow of a RedOx electrolyte in a straight conduit is investigated theoretically. Inert electrodes are deposited along segments of the opposing walls of a straight conduit that is filled with a RedOx electrolyte solution. The conduit is positioned in a uniform magnetic field. When a potential difference is applied across the opposing electrodes, the resulting current inte...

The Direct Electrochemical Investigation of Redox Enzymes

Even though the use of enzymes as useful analytical reagents when immobilized onto a transducer such as an electrochemical device has been reported in the literature for nearly two decades, the direct, i.e. unmediated electrochemistry of enzymes is, nevertheless, a rather recent development. Efforts will be made to introduce the fundamental basis for protein-surface interactions with emphas...